Get Involved
If you would like to take part in this study or would like to know more, please get in touch.
Leeds Beckett University - City Campus,
Woodhouse Lane,
LS1 3HE
Interdisciplinary Centre for Implant Research (IRIS)
APPRAISE
A Patient-reported outcome measure for PRolApse, Incontinence and meSh complication surgery (APPRAISE) is a three-year National Institute of Health Research (NIHR) funded study which will better support women to report the impact of pelvic floor surgery upon their quality of life.
APPRAISE was awarded in response to the NIHR HTA Commissioned Call 21/583 Patient reported outcome measures (PROMs) for pelvic floor disorders. This study is funded by the NIHR Health Technology Assessment Programme (NIHR152187). The views expressed are those of the author(s) and not necessarily those of the NIHR or the Department of Health and Social Care.
The challenge
Different surgical treatments are available to treat pelvic organ prolapse (POP) and stress urinary incontinence (SUI). One of these treatments uses polypropylene mesh which has led to complications requiring further corrective surgery. However, there is currently no surgical intervention-specific patient-reported outcome measure (PROM) available for these women to tell us about the effects of pelvic floor surgery on their quality of life.
Why this study is important
As a result, evidence is missing on which are the most appropriate treatments for pelvic organ prolapse (POP) and stress urinary incontinence (SUI) and their risks and complications, largely due to failings in being able to capture and record patient experiences and reports of harm over time. There is therefore a need for a PROM specific for urogynaecology surgeries to be developed to support further research into the best treatment decisions for future procedures.
Research team
The APPRAISE study is being led by Leeds Beckett University in collaboration with a large group of researchers, healthcare professionals and patients working across the University of Sheffield, University of Oxford, University of Manchester, University of Aberdeen, Sheffield Teaching Hospitals NHS Trust, Norfolk and Norwich University Hospitals NHS Foundation Trust, Epsom and St Helier University Hospitals NHS Trust, Oxford University Hospitals NHS Foundation Trust, and InSpired Health Outcomes.
- Professor Georgina Jones (APPRAISE study lead)
Professor of Health Psychology, Director of the Interdisciplinary Centre for Implant-based Research
g.l.jones@leedsbeckett.ac.uk - Professor Anne-Marie Bagnall
Professor of Health and Wellbeing Evidence, Director of the Centre for Health Promotion Research
a.bagnall@leedsbeckett.ac.uk - Dr Rhys Turner-Moore
Reader in Psychology
R.Turner-Moore@leedsbeckett.ac.uk - Dr Mollie Price
Research Fellow in Psychology
M.Price@leedsbeckett.ac.uk - Dr Kirsty Budds
Researcher in Psychology
K.M.Budds@leedsbeckett.ac.uk - Victoria Fisher
Research Fellow in Psychology
v.fisher@leedsbeckett.ac.uk - Georgina Forshall
Research Assistant and PhD student in Psychology
G.Forshall@leedsbeckett.ac.uk - Cat Brooke
Research Officer
c.brooke@leedsbeckett.ac.uk
- Professor Swati Jha (APPRAISE study co-lead)
Subspecialist Urogynaecologist, Consultant Gynaecologist, Sheffield Teaching Hospitals
swati.jha1@nhs.net - Professor Alicia O’Cathain
Professor of Health Services Research, University of Sheffield
a.ocathain@sheffield.ac.uk - Professor Crispin Jenkinson
Professor and Senior Research Fellow, University of Oxford
crispin.jenkinson@hmc.ox.ac.uk - Dr Anju Keetharuth
Health Economist, University of Sheffield
d.keetharuth@sheffield.ac.uk - Professor Donna Rowen
Professor of Health Economics, University of Sheffield
d.rowen@sheffield.ac.uk - Dr Stergios Doumouchtsis
Consultant Obstetrician, Gynaecologist and Urogynaecologist, Epsom and St Helier University Hospitals
sdoum@yahoo.com - Dr Thomas Gray
Consultant Urogynaecologist, Norfolk and Norwich University Hospitals
thomas.gray@nnuh.nhs.uk - Professor Stephen Radley
Consultant Gynaecologist and Director of Research for Obstetrics, Gynaecology and Neonatology, Sheffield Teaching Hospitals
stephen.radley@nhs.net - Dr David Churchman
Founder and Managing Director of InSpired Health Outcomes
david.churchman@inspiredoutcomes.co.uk - Professor Steve Brown
Consultant Colorectal Surgeon, University of Sheffield
steven.brown13@nhs.net - Dr Ines Rombach
Senior Research Fellow/Statistician, University of Sheffield
i.rombach@sheffield.ac.uk - Dr Abigail McNiven
Senior Qualitative Researcher in Social Geography, University of Oxford
abigail.mcniven@phc.ox.ac.uk - Dr Francine Toye
Qualitative Researcher, Oxford University Hospitals
Francine.Toye@ouh.nhs.uk - Dr Fiona Reid
Consultant Urogynaecologist, University of Manchester
fiona.reid@mft.nhs.uk - Dr Suzanne Breeman
Researcher, University of Aberdeen
s.breeman@abdn.ac.uk -
Janice Connell
Research Associate, University of Sheffield
j.connell@sheffield.ac.uk - Jean Horrocks
Patient Representative - Joanna Prance
Patient Representative
Aims
The team aims to develop a PROM to compare outcomes for the different surgical treatments to treat POP, SUI and mesh complications that captures the full range of effects on quality of life (QoL). Information about previous patient experience and long-term complications will be used to inform better support and improved services.
Methods
In this study, we will be reviewing existing research and carrying out in-depth interviews with patients who have had a variety of different surgeries for POP, SUI and mesh complications, to develop a new PROM that can better record patient experiences. We will then carry out further interviews and assessments to test how well this PROM works. We will be asking patients to feedback on the design and implementation of our research, as well as specialists in this area.
How this could benefit patients
The new questionnaire will provide a way that patient outcomes and the risks and benefits of an intervention can be measured, quantified and compared. It will also better support patients to talk about and share their lived experiences of surgery. The findings will also help inform and support healthcare professionals and policy makers to improve health services.
Header image courtesy of Freepik.com.
-
Study With us
The Graduate SchoolStudy for a research degree at Leeds Beckett and you'll join a thriving academic community in an inspiring and supportive environment. The Graduate School supports our increasingly active postgraduate research community and encourages students to make a difference to the university’s research culture and environment.
![Study With us]()
-
research with us
Research for businessLeeds Beckett University can conduct research on your behalf to help you to implement change and realise your business potential. Validating your ideas with academic evidence can be an essential part of winning contracts and fuelling business growth.
![research with us]()
